As the development and application of the fourth generation's drug dosage form

the oral colon-specific drug delivery system has the advantage of targeting orientation

increasing local drug concentration

acting on the lesion site directly

reducing drug dosage and side effect

etc.Aiming at the drug releasing mechanism

application and preparation technique

the research progress of this field is reviewed

so as to provide the theoretical basis and reference for the systematic research of the oral colon-specific drug delivery system.