Due to the unique features

such as rich self-assembly driving forces

novel self-assembly nanostructures

multiple special capabilities and good biocompatibility

short peptide based self-assembled nanomaterials are extremely attractive as building blocks for nano-biomaterials

skin care and cosmetics

drug delivery

tissue engineering scaffolds and many other applications.Because the self-assembling peptides are constituted by natural amino acids

the self-assembled nanomaterials have low cell toxicity

controlled degradation

reduced of side effects of drugs

high delivery efficiency

enhanced drug targeting property

improved gene transfection efficiency and cellular uptake rate.Therefore

there will be promising prospect for the development of peptides used as drug and gene delivery.Using the peptide based self-assembled nanomaterials as the carrier of hydrophobic anticancer drugs

protein drugs

gene and other therapeutic agents has become the research priorities of biomedical science.The progress and applications of the self-assembled peptide based nanomaterials as a loaded carrier in the biomedical science were reviewed. Moreover

the interaction mechanism and characteristics of some bioactive peptide based materials with the therapeutic agents were also introduced.