PAN Duotao, SHI Hongyan, YUAN Decheng, et al. Analysis of metabolic oscillation processes in Saccharomyces cerevisiae[J]. CIESC Journal, 2017, (3): 964-969.
PAN Duotao, SHI Hongyan, YUAN Decheng, et al. Analysis of metabolic oscillation processes in Saccharomyces cerevisiae[J]. CIESC Journal, 2017, (3): 964-969.DOI: 10.11949/j.issn.0438-1157.20161628.
Oscillation phenomenon is an inherent characteristic in biological systems and plays an important role in many dynamic bioprocesses. In order to explore the certain conditons that could possibly boost a oscillation
the metabolic pathway of the Saccharomyces cerevisiae
glycolysis were researched
and the parameters of mathmatical model was analyzed. Firstly
the simulation results associated the phase diagrams indicated that the model exists sustained oscillations with constant amplitude (limit cycle oscillations). Next
bifurcation analysis approach was used to investigate the infulence of parameters for the system producing oscillations. The results showed that several parameters of the model could lead to oscillations and the range of parameters' value was obtained
which could be applied to direct the manipulation of metabolic oscillations.