新型丝素复合膜的微结构表征及热稳定性

李莹莹; 邓谦谦; 刘浩; 刘其春; 顾正桂; 王昉

doi:10.11949/0438-1157.20191317

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新型丝素复合膜的微结构表征及热稳定性

材料化学工程与纳米技术 | 更新时间：2026-07-24

- 新型丝素复合膜的微结构表征及热稳定性
- Microstructure characterization and thermal stability of new silk fibroin composite films
- 化工学报 2020年71卷第1期页码：388-396
- 作者机构：
  
  1. 南京师范大学分析测试中心，江苏南京210023
  2. 南京师范大学化学与材料科学学院，江苏南京210023
- 作者简介：
  
  李莹莹（1994—），女，硕士研究生，liyingying0715@163.com
  王昉（1967—），女，本科，教授，wangfang@njnu.edu.cn
- 基金信息：
  
  国家自然科学基金项目(21973045;11474166);江苏省高校自然科学基金项目(15kJB150018)
- DOI：10.11949/0438-1157.20191317
  中图分类号： TQ 317
- 收稿：2019-11-04，
  
  修回：2019-11-18，
  
  网络首发：2020-08-12，
  
  纸质出版：2020-01-05
- 稿件说明：
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李莹莹, 邓谦谦, 刘浩, 刘其春, 顾正桂, 王昉. 新型丝素复合膜的微结构表征及热稳定性[J]. 化工学报, 2020, 71(1): 388-396

LI Yingying, DENG Qianqian, LIU Hao, LIU Qichun, GU Zhenggui, WANG Fang. Microstructure characterization and thermal stability of new silk fibroin composite films[J]. CIESC Journal, 2020, 71(1): 388-396
李莹莹, 邓谦谦, 刘浩, 刘其春, 顾正桂, 王昉. 新型丝素复合膜的微结构表征及热稳定性[J]. 化工学报, 2020, 71(1): 388-396 DOI： 10.11949/0438-1157.20191317.

LI Yingying, DENG Qianqian, LIU Hao, LIU Qichun, GU Zhenggui, WANG Fang. Microstructure characterization and thermal stability of new silk fibroin composite films[J]. CIESC Journal, 2020, 71(1): 388-396 DOI： 10.11949/0438-1157.20191317.

摘要

基于丝素的高分子复合材料可以广泛地应用于组织工程、生物医药和半导体材料等领域。通过物理-共混技术制备了一种新型生物高分子丝素/聚乳酸复合膜。利用扫描电镜、傅里叶红外光谱、拉曼光谱、X射线衍射和热分析技术对其形貌、结构和相态组分以及热稳定性进行了表征，探究了不同比例复合膜的微结构、相互作用机理和热稳定性。结果表明：随着丝素含量的增加，复合膜中的β-折叠含量增多，α-螺旋和无规卷曲含量减少，玻璃化转变温度提高；由于丝素与聚乳酸间的相互作用，提高了复合膜的热稳定性。

Abstract

Silk fibroin-based polymer composites can be widely used in the fields of tissue engineering

biomedicine

and semiconductor materials. In this study

a novel silk fibroin/polylactic acid biocomposite film was prepared by physical-blending technique. Scanning electron microscope(SEM)

Fourier transform infrared analysis(FTIR)

Raman spectroscopy

X-ray diffraction (XRD) and thermal analysis were used to characterize the morphology

structure

phase components and thermal stability of the composite films with different proportions

and to explore their microstructure

interaction mechanism and thermal stability. The results showed that with the increase of silk fibroin content

the content of β-sheet increased

the content of α-helix and random coils decreased

and the glass transition temperature increased. Due to the interaction between silk fibroin and polylactic acid

which improved the thermal stability of the composite film.

关键词

Keywords

references

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