凝胶对结晶过程影响的研究进展

张文铖; 龚俊波; 董伟兵; 吴送姑

doi:10.11949/0438-1157.20190754

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凝胶对结晶过程影响的研究进展

综述与专论 | 更新时间：2026-07-24

- 凝胶对结晶过程影响的研究进展
- Research progress in effect of gel on crystallization process
- 化工学报 2020年71卷第2期页码：487-499
- 作者机构：
  
  1. 天津大学化学工程联合国家重点实验室, 天津 300072
  2. 青海民族大学化学化工学院, 青海,西宁 810007
- 作者简介：
  
  张文铖（1995—），男，硕士研究生，614304838@qq.com
  吴送姑（1987—），女，博士，讲师，wusonggu@tju.edu.cn
- 基金信息：
  
  国家自然科学基金项目(21808158);中国博士后自然科学基金项目(2018M641651);青海民族大学自然科学基金项目(2019-XJZD01)
- DOI：10.11949/0438-1157.20190754
  中图分类号： TQ 420.6⁺1
- 收稿：2019-07-02，
  
  修回：2019-10-17，
  
  网络首发：2020-08-14，
  
  纸质出版：2020-02-05
- 稿件说明：
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张文铖, 龚俊波, 董伟兵, 吴送姑. 凝胶对结晶过程影响的研究进展[J]. 化工学报, 2020, 71(2): 487-499

ZHANG Wencheng, GONG Junbo, DONG Weibing, WU Songgu. Research progress in effect of gel on crystallization process[J]. CIESC Journal, 2020, 71(2): 487-499
张文铖, 龚俊波, 董伟兵, 吴送姑. 凝胶对结晶过程影响的研究进展[J]. 化工学报, 2020, 71(2): 487-499 DOI： 10.11949/0438-1157.20190754.

ZHANG Wencheng, GONG Junbo, DONG Weibing, WU Songgu. Research progress in effect of gel on crystallization process[J]. CIESC Journal, 2020, 71(2): 487-499 DOI： 10.11949/0438-1157.20190754.

摘要

相比于传统的溶液相结晶，凝胶用作结晶介质时，由于能抑制对流和减慢溶质分子的扩散，除了能提供较大的过饱和度且不会导致爆发成核，以及使溶质分子在生长面上连续地生长之外，还可以通过设计特定的凝胶剂为溶质分子提供模板或者活性成核位点，这使得凝胶相结晶成为了一种有效的结晶控制手段，引起了研究人员的广泛关注。综述了高分子凝胶、超分子凝胶以及无机凝胶如何有效地控制结晶成核和生长的速度，调控晶型、晶习和晶体粒度，简单介绍了微凝胶在溶液相结晶中的作用，以及凝胶相结晶未来的发展趋势。

Abstract

Compared with the traditional solution phase crystallization

when the gel is used as a crystallization medium

it can suppress convection and reduce the diffusion of the solute molecules. So a high supersaturation without causing explosive nucleation can be obtained and allowing the solute molecules continuous growth on the crystal surface. Gel is also possible to provide as a template or active nucleation sites by designing a specific gel agent. It makes the crystallization in gel is an effective control means and causes extensive attention. This paper reviews how polymer gel

supramolecular gels and inorganic gels can effectively control the nucleation and growth rate

regulate polymorphism

crystal habit and particle size. The role of microgels in solution phase crystallization and the future development trend of gel phase crystallization are briefly introduced.

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references

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