RAFT聚合制备PMPS-<italic style="font-style: italic">b</italic>-PNIPAM嵌段共聚物及温敏性纳米粒子

赵小燕; 单国荣

doi:10.11949/0438-1157.20190342

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RAFT聚合制备PMPS-b-PNIPAM嵌段共聚物及温敏性纳米粒子

材料化学工程与纳米技术 | 更新时间：2026-07-24

- RAFT聚合制备PMPS-b-PNIPAM嵌段共聚物及温敏性纳米粒子
- PMPS-b-PNIPAM copolymers synthesized by RAFT polymerization and their thermo-responsive nanoparticles
- 化工学报 2019年70卷第10期页码：4080-4088
- 作者机构：
  
  1.化学工程联合国家重点实验室，浙江大学化学工程与生物工程学院，浙江杭州 310027
  2.浙江大学衢州研究院，浙江衢州 324000
- 作者简介：
  
  赵小燕（1992—），女，博士研究生，xiaoyanzhao161@163.com
  单国荣（1968—），男，博士，教授，shangr@zju.edu.cn
- 基金信息：
- DOI：10.11949/0438-1157.20190342
  中图分类号： TQ 316.344
- 收稿：2019-04-02，
  
  修回：2019-05-29，
  
  网络首发：2026-07-24，
  
  纸质出版：2019-10-05
- 稿件说明：
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赵小燕, 单国荣. RAFT聚合制备PMPS-b-PNIPAM嵌段共聚物及温敏性纳米粒子[J]. 化工学报, 2019, 70(10): 4080-4088

ZHAO Xiaoyan, SHAN Guorong. PMPS-b-PNIPAM copolymers synthesized by RAFT polymerization and their thermo-responsive nanoparticles[J]. CIESC Journal, 2019, 70(10): 4080-4088
赵小燕, 单国荣. RAFT聚合制备PMPS-b-PNIPAM嵌段共聚物及温敏性纳米粒子[J]. 化工学报, 2019, 70(10): 4080-4088 DOI： 10.11949/0438-1157.20190342.

ZHAO Xiaoyan, SHAN Guorong. PMPS-b-PNIPAM copolymers synthesized by RAFT polymerization and their thermo-responsive nanoparticles[J]. CIESC Journal, 2019, 70(10): 4080-4088 DOI： 10.11949/0438-1157.20190342.

摘要

利用可逆加成-断裂链转移(RAFT)活性自由基聚合合成了一系列分子量可控、分子量分布窄的甲基丙烯酸-3-三甲氧基硅丙酯(MPS)和

-异丙基丙烯酰胺(NIPAM)的嵌段共聚物，在水溶液中分散制备温敏性的含硅纳米粒子。保持疏水链段PMPS的长度恒定，改变亲水链段PNIPAM的长度，在不同pH的水溶液中进行实验，研究亲水链段长度、pH对聚合物的临界聚集浓度、纳米粒子的尺寸和形貌以及温度变化过程中的相分离行为的影响，得到尺寸较小、溶液稳定的温度响应性含硅纳米粒子，同时具有有机物和无机物的优良特点，在生物医学、化学催化、纳米反应器、染料涂料等多领域具有广泛的应用前景。

Abstract

A series of molecular weight-controlled

narrow molecular weight distributions of 3-trimethoxysilyl methacrylate (MPS) and

-isopropyl acrylamide (NIPAM) block copolymers were synthesized by reversible addition-fragmentation chain transfer (RAFT) living radical polymerization. Temperature-sensitive silicon-containing nanoparticle are prepared by dispersing in aqueous solution. With the same chain length of hydrophobic segment PMPS

by changing the chain length of hydrophilic segment PNIPAM and the pH of the water solutions

the critical aggregation concentrations

the diameters and morphologies of the nanoparticles

and the phase separation behavior happening in the process of temperature variation were studied. Thermo-responsive and spherical nanoparticles were attained. The nanoparticles possessed advantages of both organics and inorganics. And they may have wide applications in many fields such as biomedicine

chemical catalysis

nanoreactors

dyes

coatings and so on.

关键词

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references

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RAFT聚合制备PMPS-b-PNIPAM嵌段共聚物及温敏性纳米粒子

PMPS-b-PNIPAM copolymers synthesized by RAFT polymerization and their thermo-responsive nanoparticles

DOI：10.11949/0438-1157.20190342

摘要

Abstract

关键词

Keywords

references