FAN Daidi, DUAN Mingrui, MI Yu, et al. HIGH DENSITY FERMENTATION OF RECOMBINANT E.coli FOR PRODUCTION OF HUMAN-LIKE COLLAGEN[J]. CIESC Journal, 2002, (7).
FAN Daidi, DUAN Mingrui, MI Yu, et al. HIGH DENSITY FERMENTATION OF RECOMBINANT E.coli FOR PRODUCTION OF HUMAN-LIKE COLLAGEN[J]. CIESC Journal, 2002, (7).DOI:
重组E.coli工程菌高密度培养生产人源型胶原蛋白
摘要
Abstract
Several technical parameters were studied during the fermentation of recombinant E.coli for the production of collagen-like biopolymer.The effects of dissolved oxygen as well as glucose concentration on fermentation were observed.The OD 600 value could reach 98 when dissolved oxygen was controlled at 50% and glucose around 1%.The production of human-like collagen with a yield of 29.4% was obtained.