Fe/attapulgite and Zn/attapulgite desulfurizer were prepared by loading Fe and Zn element on attapulgite by precipitation.The desulfurizers were characterized by XRD，TEM and TPR.The stability of desulfurizers in ammonia water and hydrochloric acid was studied.Additionally，the changes of concentration of H2S in the off-gas were investigated in the sweetening process and the desulfurization capacities of two desulfurizers were compared.The influence of grain size，load amount and self-regeneration times on desulfurization capacity of Fe/attapulgite was studied.The results showed that active components were loaded on the surface of attapulgite uniformly.Fe/attapulgite had good desulfurization capability and self-reset capability，and its desulfurization capacity was 120 times that of active carbon and 7.67 times that of Zn/attapulgite.Decrease of grain size and increase of load amount could increase desulfurization capacity but regeneration by itself could only recover part of desulfurization capacity.Fe/attapulgite desulfurizer has wide application as a good desulfurizer.