Aiming at the great difficulty in crude oil unit (CDU) operation for the diversity of crude oil

an advanced process control comprehensive scheme is presented

which composed of both decreasing the property variety of crude oil feedin and introducing parameters reflecting property into soft sensor and controller.By scheduling and blending the optimization of multiple crude oils to be refined

the blended crude oil feed-in has relatively steady properties and has small influence on parameters of the unit operation

hence the disturbance from the change in operating point is decreased remarkably.On the other hand

for the remaining small property variety of blended crude oil

the parameters reflecting property are introduced to soft sensor calculation and advanced process controller based on model predictive control to overcome the disturbance of property variety.By scheduling and blending optimization

the parameter varieties of unit operation are small

which makes it possible that the soft sensor and predictive control using linear approximate model have a great performance.Application on a CDU with multiple crude oils shows the validity of the comprehensive scheme.