A novel static micromixer was proposed which was designed according to the characteristics of mixing liquids on the micro-scale.The device was fabricated on glass substrates using wet-etching technique.By applying a steady axial pressure gradient

staggered oriented ridges arranged periodically in the microchannel could generate transverse and three dimensional flow.Chaotic advection was induced in the microchannel

and then stretched and folded material interface and enhanced fluid mixing.The computational fluid dynamics(CFD)method was used to analyze the chaotic mixing in the micromixer.Red dye mixing experiments were carried out to visualize the development of mixing process and the performance in the micromixer.Experimental investigation demonstrated that the design enhanced mixing at both low and high Reynolds number.