Molecular imprinting technology (MIT) with predetermination

specific recognition and practicability is widely used in the domain of biosensor

membrane and isomer separation

antibody mimics

enzyme-mimic catalyst and solid phase extraction (SPE).SPE is a better，more simple and more convenient separation technology than liquid-liquid extraction

and has developed rapidly in recent three decades.It is a hopeful domain that uses molecularly imprinted polymers as solid phase extraction packing (MISPE).In this paper

a brief introduction is given about the origin

principle and methods of molecular imprinting technology and solid phase extraction.MISPE for the purpose of environmental sample analysis

medicine separation

pharmaceutical analysis

clinical inspection

and others is emphasized.The achievement

existent problem and trend of MISPE are also reviewed.76 references are cited.