In this work，a novel method of synthesizing reaction paths while considering influence of kinetics and environmental constraints is presented. A concept of equilibrium temperature interval is used to estimate kinetic attributes of reactions. Under a set of given raw materials and desired products

a set of potential intermediate chemicals

joint products are chosen through chemical reasoning on the basis of atoms and functional groups constituting the raw materials available. The reaction path network is generated with the atom balance equation obtained. Then some fuzzy rules are used to evaluate each reaction’s equilibrium temperature interval. Finally

a fuzzy model is solved to get all fuzzy objects such as economic and environmental object for each reaction

and a multi-objective programming problem is solved to get a series of reaction paths including the best pathway.