A knowledge based geneticsimulatedannealing method for optimizing the tube circuit of finandtube heat exchangers was presented by introducing specialized knowledge and the simulated annealing method into the existing method.Case studies were performed on a practical finandtube heat exchangerThe optimization target is to obtain maximum heat exchange capacity of the heat exchanger with the constraint conditions of practical manufactureThe test results showed that after optimization;all paths of the optimal tube circuit were uniformly distributed in the airflow field and contained equal number of tubes;and the imbalance of heat transfer among the paths was avoidedThe heat exchange capacity of the heat exchanger was 22% larger than that before optimization;and was 103% larger than that obtained by the existing puregeneticalgorithmbased optimization method.