Process simulation design and techno-economic analysis of production technology of glycerol dehydrogenase

ZENG Hong; FANG Baishan; WANG Paifen; ZHANG Tingting

doi:10.3969/j.issn.0438-1157.2013.06.036

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Process simulation design and techno-economic analysis of production technology of glycerol dehydrogenase

更新时间：2025-12-10

- Process simulation design and techno-economic analysis of production technology of glycerol dehydrogenase
- CIESC Journal Issue 6, Pages: 2169-2176(2013)
- 作者机构：
  
  1. 华侨大学化工学院,福建,厦门,361021
  2. 泉州师范学院化学与生命科学学院,福建,泉州,362000
  3. 厦门大学化学化工学院,福建,厦门,361005
  4. 厦门大学醇醚酯化工清洁生产国家工程实验室,福建,厦门,361005
- 作者简介：
- 基金信息：
- DOI：10.3969/j.issn.0438-1157.2013.06.036
  CLC： Q018TH162T-9
- Online First：05 June 2013，
  
  Published：05 June 2013
- 稿件说明：
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ZENG Hong, FANG Baishan, WANG Paifen, et al. Process simulation design and techno-economic analysis of production technology of glycerol dehydrogenase[J]. CIESC Journal, 2013, (6): 2169-2176.
DOI：

ZENG Hong, FANG Baishan, WANG Paifen, et al. Process simulation design and techno-economic analysis of production technology of glycerol dehydrogenase[J]. CIESC Journal, 2013, (6): 2169-2176. DOI： 10.3969/j.issn.0438-1157.2013.06.036.

摘要

Abstract

Glycerol dehydrogenase (GDH) is one of the key enzymes for production of dihydroxyacetone (DHA) and 1

3-propanediol (PDO) by the enzymatic method.Based on scale-up of laboratory experiment

the Superpro Designer® emluator was used to design and simulate the whole process of industrial technology for GDH production

by coupling with costing and economic evaluation of flowsheeting.Simulation results indicated that the process design was reasonable with main process data in agreement with experimental results.The economic analysis showed that raw materials and supplies shared the larger proportion of operating cost reaching 16% and 60% respectively.The expected return on investment (ROI) was to reach 50.48% of approximately 75.36 million CNY project total investments of a 17.9 t·a-1 plant

as the after-tax profits about 21.08 million CNY·a-1.

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