Oral colon-specific drug delivery system and its preparation

WU Qingxi; YAO Shanjing

doi:10.3969/j.issn.0438-1157.2013.01.023

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Oral colon-specific drug delivery system and its preparation

更新时间：2025-12-10

- Oral colon-specific drug delivery system and its preparation
- CIESC Journal Issue 1, Pages: 210-222(2013)
- 作者机构：
  
  浙江大学生物质化工教育部重点实验室,化学工程与生物工程学系,浙江,杭州,310027
- 作者简介：
- 基金信息：
- DOI：10.3969/j.issn.0438-1157.2013.01.023
  CLC： 819
- Online First：05 January 2013，
  
  Published：05 January 2013
- 稿件说明：
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WU Qingxi, YAO Shanjing. Oral colon-specific drug delivery system and its preparation[J]. CIESC Journal, 2013, (1): 210-222.
DOI：

WU Qingxi, YAO Shanjing. Oral colon-specific drug delivery system and its preparation[J]. CIESC Journal, 2013, (1): 210-222. DOI： 10.3969/j.issn.0438-1157.2013.01.023.

摘要

口服结肠靶向给药系统作为第四代药物剂型的发展和应用

具有靶向定位性、可提高局部药物浓度、直接作用于病变部位、降低药物剂量、减少副反应等优点

因而备受研究者的关注。本文针对口服结肠靶向给药系统的给药机理、应用和制备技术

综述了该领域近些年来的研究进展

为系统研究口服结肠靶向给药系统提供理论依据和参考。

Abstract

As the development and application of the fourth generation's drug dosage form

the oral colon-specific drug delivery system has the advantage of targeting orientation

increasing local drug concentration

acting on the lesion site directly

reducing drug dosage and side effect

etc.Aiming at the drug releasing mechanism

application and preparation technique

the research progress of this field is reviewed

so as to provide the theoretical basis and reference for the systematic research of the oral colon-specific drug delivery system.

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