Recent advances in efficient lignin depolymerization: strategies, mechanisms, and product valorization

WANG Jiajia; WANG Xiaofei; WANG Yali; MA Kun; WANG Yuqi; WU Le; DING Xin

doi:10.11949/0438-1157.20260817

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Recent advances in efficient lignin depolymerization: strategies, mechanisms, and product valorization

更新时间：2026-08-20

- Recent advances in efficient lignin depolymerization: strategies, mechanisms, and product valorization
- CIESC Journal (2026)
- 作者机构：
  
  1.西北大学化工学院，陕西西安710127
  2.西安市绿色氢能制储用一体化技术重点实验室，陕西西安710127
- 作者简介：
- 基金信息：
- DOI：10.11949/0438-1157.20260817
  CLC： TQ 35
- Received：13 June 2026，
  
  Revised：2026-08-19，
  
  Accepted：20 August 2026，
- 稿件说明：
移动端阅览
WANG Jiajia, WANG Xiaofei, WANG Yali, et al. Recent advances in efficient lignin depolymerization: strategies, mechanisms, and product valorization[J/OL]. CIESC Journal, 2026.
DOI：

WANG Jiajia, WANG Xiaofei, WANG Yali, et al. Recent advances in efficient lignin depolymerization: strategies, mechanisms, and product valorization[J/OL]. CIESC Journal, 2026. DOI： 10.11949/0438-1157.20260817.

摘要

木质素作为自然界中储量最丰富的可再生芳香族聚合物，如何实现其高效解聚与解聚产物高值转化利用对替代化石资源、构建可持续生物经济体系至关重要。本工作就近年来研究者在木质素高效解聚及解聚单体高值转化利用方面取得的突出成果进行系统综述。首先，在木质素高效解聚方面，重点讨论了如何通过精准构筑催化活性位点以实现关键化学键（如β-O-4、C

-C

等）的选择性断裂，并调控中间产物反应路径，以有效提升芳香族单体的产率与选择性。其次，在解聚单体高值利用方面，重点讨论了解聚单体产物转化为芳烃燃料、高附加值化学品、聚合物前体及功能材料等多种应用场景。本综述能够为木质素高效转化利用的催化剂设计、反应过程优化及工业化应用提供重要借鉴。

Abstract

Lignin

the most abundant renewable aromatic polymer in nature

possesses a highly complex structure and strong resistance to depolymerization.

Achieving its efficient depolymerization and the high-value utilization of the resulting products is of critical importance for reducing dependence on fossil resources and establishing a sustainable bioeconomy. This review systematically summarizes the significant advances made in recent years in the efficient depolymerization of lignin and the valorization of lignin-derived monomeric products. First

with respect to lignin depolymerization

particular emphasis is placed on the precise engineering of catalytic active sites to enable the selective cleavage of key chemical bonds (e.g.

β-O-4 and C

-C

linkages)

while simultaneously regulating the reaction pathways of intermediate species to enhance the yield and selectivity of aromatic monomers. Second

regarding the high-value utilization of depolymerized monomers

this review highlights their conversion into aromatic fuels

value-added chemicals

polymer precursors

and functional materials across a broad range of application scenarios. The insights presented herein provide important guidance for catalyst design

reaction process optimization

and the industrial implementation of lignin valorization technologies

while also identifying promising directions for the future green and sustainable development of this field.

关键词

Keywords

references

Rath S , Pradhan D , Du H S , et al . Transforming lignin into value-added products: Perspectives on lignin chemistry, lignin-based biocomposites, and pathways for augmenting ligninolytic enzyme production [J ] . Advanced Composites and Hybrid Materials , 2024 , 7 ( 1 ): 27 .

Jiju P S , Patel A K , Shruthy N S , et al . Sustainability through lignin valorization: recent innovations and applications driving industrial transformation [J ] . Bioresources and Bioprocessing , 2025 , 12 ( 1 ): 88 .

魏剑 . 木质素结构及其氢解制备芳烃 [D ] . 北京：北京化工大学 , 2025 .

Wei J . Structure of lignin and its hydrogenolysis to aromatic hydrocarbons [D ] . Beijing : Beijing University of Chemical Technology , 2025 .

曹美芳 . 铌钨氧化物负载金属催化剂的制备及其在木质素氢解中的应用 [D ] . 广州：华南理工大学 , 2024 .

Cao M F . Preparation of niobium tungsten oxide supported metal catalyst and its application in hydrogenolysis of lignin [D ] . Guangzhou : South China University of Technology , 2024 .

Zhang B , Meng Q L , Liu H Z , et al . Catalytic conversion of lignin into valuable chemicals: full utilization of aromatic nuclei and side chains [J ] . Accounts of Chemical Research , 2023 , 56 ( 24 ): 3558 - 3571 .

龙金星 , 徐莹 , 王铁军 , 等 . 木质素催化解聚与氢解 [J ] . 新能源进展 , 2014 , 2 ( 2 ): 83 - 88 .

Long J X , Xu Y , Wang T J , et al . Catalytic depolymerization and hydrogenolysis of lignin [J ] . Advances in New and Renewable Energy , 2014 , 2 ( 2 ): 83 - 88 .

Chen M J , Li Y D , Lu F C , et al . Lignin hydrogenolysis: phenolic monomers from lignin and associated phenolates across plant clades [J ] . ACS Sustainable Chemistry & Engineering , 2023 , 11 ( 27 ): 10001 - 10017 .

Wang S Z , Li X C , Ma R M , et al . Catalytic hydrogenolysis of lignin into serviceable products [J ] . Accounts of Chemical Research , 2025 , 58 ( 4 ): 529 - 542 .

刘家鹏 . 木质素在供氢溶剂中高效解聚制备酚类化学品的研究 [D ] . 北京：北京化工大学 , 2023 .

Liu J P . Study on efficient depolymerization of lignin in hydrogen donor solvents for the preparation of phenolic chemicals [D ] . Beijing : Beijing University of Chemical Technology , 2023 .

胡育珍 , 张琦 , 王晨光 , 等 . 木质素催化氧化解聚研究进展 [J ] . 高校化学工程学报 , 2019 , 33 ( 3 ): 505 - 515 .

Hu Y Z , Zhang Q , Wang C G , et al . Progress in catalytic oxidative depolymerization of lignin [J ] . Journal of Chemical Engineering of Chinese Universities , 2019 , 33 ( 3 ): 505 - 515 .

孔劼琛 , 骆治成 , 李博龙 , 等 . 木质素解聚和加氢脱氧的进展 [J ] . 中国科学(化学) , 2015 , 45 ( 5 ): 510 - 525 .

Kong J C , Luo Z C , Li B L , et al . Advances in depolymerization and hydrodeoxygenation of lignin [J ] . SCIENTIA SINICA Chimica , 2015 , 45 ( 5 ): 510 - 525 .

Tan Z Q , Li Y Y , Chen F F , et al . Challenges and perspectives of the conversion of lignin waste to high-value chemicals by pyrolysis [J ] . Processes , 2024 , 12 ( 3 ): 589 .

Ali S , Rani A , Dar M A , et al . Recent advances in characterization and valorization of lignin and its value-added products: challenges and future perspectives [J ] . Biomass , 2024 , 4 ( 3 ): 947 - 977 .

Yang C R , Qin J X , Sun S X , et al . Progress in developing methods for lignin depolymerization and elucidating the associated mechanisms [J ] . European Polymer Journal , 2024 , 210 : 112995 .

陈冰玉 , 邸明伟 . 木质素解聚研究新进展 [J ] . 高分子材料科学与工程 , 2019 , 35 ( 6 ): 157 - 164 .

Chen B Y , Di M W . Progress on research of depolymerization of lignin [J ] . Polymer Materials Science & Engineering , 2019 , 35 ( 6 ): 157 - 164 .

Sun Z H , Fridrich B , de Santi A , et al . Bright side of lignin depolymerization: toward new platform chemicals [J ] . Chemical Reviews , 2018 , 118 ( 2 ): 614 - 678 .

Obrzut N , Hickmott R , Shure L , et al . The effects of lignin source and extraction on the composition and properties of biorefined depolymerization products [J ] . RSC Sustainability , 2023 , 1 ( 9 ): 2328 - 2340 .

Wang X , Xu W B , Zhang D , et al . Structural characteristics-reactivity relationships for catalytic depolymerization of lignin into aromatic compounds: a review [J ] . International Journal of Molecular Sciences , 2023 , 24 ( 9 ): 8330 .

Palumbo C T , Ouellette E T , Zhu J , et al . Accessing monomers from lignin through carbon–carbon bond cleavage [J ] . Nature Reviews Chemistry , 2024 , 8 ( 11 ): 799 - 816 .

Abu-Omar M M , Barta K , Beckham G T , et al . Guidelines for performing lignin-first biorefining [J ] . Energy & Environmental Science , 2021 , 14 ( 1 ): 262 - 292 .

Rinaldi R , Jastrzebski R , Clough M T , et al . Paving the way for lignin valorisation: recent advances in bioengineering, biorefining and catalysis [J ] . Angewandte Chemie International Edition , 2016 , 55 ( 29 ): 8164 - 8215 .

Liu X D , Bouxin F P , Fan J J , et al . Recent advances in the catalytic depolymerization of lignin towards phenolic chemicals: a review [J ] . ChemSusChem , 2020 , 13 ( 17 ): 4296 - 4317 .

Saini K , Kumar A , Biswas B , et al . Low-temperature alkali lignin depolymerization to functional chemicals [J ] . Biomass Conversion and Biorefinery , 2022 , 12 ( 1 ): 209 - 219 .

Xu Q , Xiao L P , Wang Q , et al . Efficient hydrogenolysis of woody plant lignin into phenolic compounds over a CuO/CeO 2 catalyst [J ] . Journal of Catalysis , 2024 , 435 : 115552 .

Liu Z Q , Yu Y Y , Liu Y J , et al . Unlocking birch lignin hydrocracking through tandem catalysis: unraveling the role of moderate hydrogen spillover [J ] . ACS Catalysis , 2024 , 14 ( 3 ): 2115 - 2126 .

Wang S Z , Li X C , Fu C , et al . Atomically dispersed palladium driving reductive catalytic fractionation of lignocellulose into alkene-functionalized phenols [J ] . ACS Catalysis , 2024 , 14 ( 5 ): 3565 - 3574 .

Wang N , Deng Y X , Liao Z J , et al . Al-doped silica nanospheres supported Ni catalyst for active sites modulating in the reductive depolymerization of technical lignin [J ] . Chemical Engineering Journal , 2026 , 537 : 176364 .

Zhang X , Jiang Y H , Li W Z , et al . Production of liquid fuels via catalytic transfer hydrogenation promoting lignin depolymerization on modified Y zeolite: Formic acid as a continuous hydrogen source [J ] . Energy Conversion and Management , 2024 , 302 : 118144 .

Dolan D , Brucato R , Reid C , et al . Selective lignin depolymerization via transfer hydrogenolysis using Pd/hydrotalcite catalysts: model compounds to whole biomass [J ] . Chemical Science , 2024 , 15 ( 48 ): 20223 - 20239 .

Zhou H , Liu X H , Guo Y , et al . Self-hydrogen supplied catalytic fractionation of raw biomass into lignin-derived phenolic monomers and cellulose-rich pulps [J ] . JACS Au , 2023 , 3 ( 7 ): 1911 - 1917 .

Shen X J , Zhao Z T , Wen J L , et al . Standardization transformation of C-lignin to catechol and propylene [J ] . Nature Communications , 2025 , 16 : 6245 .

Chen M Q , Li H , Wang Y S , et al . Lignin depolymerization for aromatic compounds over Ni-Ce/biochar catalyst under aqueous-phase glycerol [J ] . Applied Energy , 2023 , 332 : 120489 .

罗柏文 . 生物炭包覆钴基催化剂的设计与制备及其在木质素还原解聚中的应用 [D ] . 广州：广东工业大学 , 2025 .

Luo B W . Design and synthesis of biochar-encapsulated cobalt catalysts for lignin reductive depolymerization [D ] . Guangzhou : Guangdong University of Technology , 2025 .

Zhu L Y , Li W Z , Zhang H , et al . Bimetallic ruthenium- and zinc-doped beta zeolite for efficiently depolymerizing Kraft lignin [J ] . Fuel , 2023 , 349 : 128766 .

Ogunbiyi A T , Li W Z , Zhu L Y , et al . Moderated molybdenum-zeolite interaction and tunable lewis-Brønsted acid sites’ synergy for efficient kraft lignin depolymerization in solvent-donated hydrogen [J ] . Energy & Fuels , 2025 , 39 ( 23 ): 11159 - 11172 .

Ogunbiyi A T , Li W Z , Hamza A , et al . Harnessing hydrogen activation capability and Lewis acidity in bimetallic Mo-W/H-Beta catalysts for enhanced lignin depolymerization [J ] . Journal of Catalysis , 2026 , 453 : 116542 .

Qiu S K , Wu Z P , Liu X D , et al . Selective catalytic depolymerization of lignin to targeted phenolic monomers using noble metals supported on MgAl 2 O 4 without external hydrogen [J ] . Journal of Agricultural and Food Chemistry , 2025 , 73 ( 36 ): 22540 - 22553 .

舒日洋 , 徐莹 , 张琦 , 等 . 木质素催化解聚的研究进展 [J ] . 化工学报 , 2016 , 67 ( 11 ): 4523 - 4532 .

Shu R Y , Xu Y , Zhang Q , et al . Progress in catalytic depolymerization of lignin [J ] . CIESC Journal , 2016 , 67 ( 11 ): 4523 - 4532 .

张颖 , 翟勇祥 . 木质素的催化加氢转化 [J ] . 化工学报 , 2017 , 68 ( 3 ): 821 - 830 .

Zhang Y , Zhai Y X . Catalytic hydroprocessing of lignin [J ] . CIESC Journal , 2017 , 68 ( 3 ): 821 - 830 .

胡珺 . 木质素定向解聚制备单酚类化合物的研究 [D ] . 南京：东南大学 , 2016 .

Hu J . Study on depolymerization of lignins into monomeric phenolic compounds [D ] . Nanjing : Southeast University , 2016 .

沈晓骏 , 黄攀丽 , 文甲龙 , 等 . 木质素氧化还原解聚研究现状 [J ] . 化学进展 , 2017 , 29 ( 1 ): 162 - 178 .

Shen X J , Huang P L , Wen J L , et al . Research status of lignin oxidative and reductive depolymerization [J ] . Progress in Chemistry , 2017 , 29 ( 1 ): 162 - 178 .

万欢爱 , 盛志远 , 邵礼书 , 等 . 催化氧化法解聚木质素生产高值化学品的研究进展 [J ] . 生物加工过程 , 2024 , 22 ( 1 ): 1 - 8, 32 .

Wan H A , Sheng Z Y , Shao L S , et al . Progress on value-added chemicals from lignin through catalytic oxidative depolymerization [J ] .

Chinese Journal of Bioprocess Engineering , 2024 , 22 ( 1 ): 1 - 8, 32 .

Gu N X , Palumbo C T , Bleem A C , et al . Autoxidation catalysis for carbon–carbon bond cleavage in lignin [J ] . ACS Central Science , 2023 , 9 ( 12 ): 2277 - 2285 .

Zhao L Y , Wang S M , Li X Y , et al . Selective oxidative depolymerization of lignin into aromatic monomers using a palladium-doped polyoxometalate catalyst [J ] . International Journal of Biological Macromolecules , 2025 , 311 : 143644 .

李立霞 . 多级孔分子筛负载铜基催化剂的制备及其催化木质素选择性氧化解聚 [D ] . 广州：华南理工大学 , 2020 .

Li L X . Preparation of copper-supported hierarchical zeolite catalyst for selectively catalytic oxidative depolymerization of lignin [D ] . Guangzhou : South China University of Technology , 2020 .

Palumbo C T , Gu N X , Bleem A C , et al . Catalytic carbon–carbon bond cleavage in lignin via manganese–zirconium-mediated autoxidation [J ] . Nature Communications , 2024 , 15 : 862 .

Peng W B , Bao H X , Wang Y G , et al . Selective depolymerization of lignin towards isolated phenolic acids under mild conditions [J ] . ChemSusChem , 2023 , 16 ( 20 ): e202300750 .

Tang C , Cao Y , Gao J , et al . Oxidative catalytic depolymerization of lignin into value-added monophenols by carbon nanotube-supported Cu-based catalysts [J ] . Molecules , 2024 , 29 ( 19 ): 4762 .

Liu X T , Jiang Z J , Cao X R , et al . Z-scheme heterojunction g-C 3 N 4 /CQD/CdZnS with high redox capability for enhancing visible light-driven photocatalytic depolymerization of lignin into aromatic monomers [J ] . Green Chemistry , 2024 , 26 ( 4 ): 1935 - 1948 .

He G H , Hu J H , Sun C Y , et al . Advances in photocatalytic lignin depolymerization: photocatalytic materials and mechanisms [J ] . Journal of Wood Chemistry and Technology , 2024 , 44 ( 2 ): 65 - 87 .

吴可嘉 . 氧缺陷型催化剂光驱动木质素氧化解聚 [D ] . 广州：华南理工大学 , 2024 .

Wu K J . Photocatalytic oxidative conversion of lignin over oxygen-deficient catalysts [D ] . Guangzhou : South China University of Technology , 2024 .

Han S , Zhao Y , Liang M N , et al . A mesoporous TiO 2 /carbon dot heterojunction photocatalyst efficiently cleaves entire types of C–O bonds in lignin under visible light [J ] . Green Chemistry , 2025 , 27 ( 29 ): 8883 - 8900 .

Jiang H T , Yang W C , Lian X , et al . S-scheme Cs 3 Bi 2 Br 9 /Bi 2 WO 6 heterojunctions for efficient photocatalytic cleavage of C–C bonds in β-1 lignin models [J ] . Journal of Materials Chemistry A , 2024 , 12 ( 42 ): 28744 - 28752 .

Liang J K , Han J Y , Zhou M , et al . Ultrasonic-enhanced photocatalysis through piezoelectric and cavitation effects for lignin depolymerization [J ] . International Journal of Biological Macromolecules , 2024 , 264 : 130526 .

Ma Z M , Zhang L , Zang L H , et al . Modification of G-C 3 N 4 by the surface alkalinization method and its photocatalytic depolymerization of lignin [J ] . Materials , 2025 , 18 ( 14 ): 3350 .

Dai D L , Qiu J H , Xia G L , et al . Defect engineering promoted photocatalysis for lignin depolymerization: performance and mechanism insight [J ] . ACS Catalysis , 2023 , 13 ( 22 ): 14987 - 14995 .

Geng X L , Wang B J , Jia Y , et al . Enhanced photocatalysis efficiency of flower-like Ni/ZnIn 2 S 4 coupling with supplying-hydrogen alcohols to catalyze lignin β-O-4 models into aromatic monomers [J ] . Renewable Energy , 2025 , 251 : 123428 .

Qin Q , Liu W Q , Xia Z H , et al . Efficient and selective C–C bond cleavage of lignin into aromatic derivatives on Cs 3 Sb 2 Br 9 nanocrystal photocatalysts [J ] . Advanced Functional Materials , 2025 , 35 ( 44 ): 2504563 .

Jiang H T , Liu M X , Lian X , et al . CsPbBr 3 quantum dots promoted depolymerization of oxidized lignin via photocatalytic semi-hydrogenation/reduction strategy [J ] . Angewandte Chemie International Edition , 2024 , 63 ( 7 ): e202318850 .

Hu X , Ribadeau-Dumas L , Nevado C . Redox-neutral photocatalytic cleavage and gem-difluoroalkenylation of lignin linkages [J ] . Science Advances , 2025 , 11 ( 33 ): eady2227 .

Wang J Q , Li Y X , Liu H , et al . Depolymerization of native lignin over thiol capped ultrathin ZnIn 2 S 4 microbelts mediated by photogenerated thiyl radical [J ] . Angewandte Chemie International Edition , 2024 , 63 ( 37 ): e202410397 .

Liu X , Wang Y , Duan H H . Recent progress in electrocatalytic conversion of lignin: from monomers, dimers, to raw lignin [J ] . Precision Chemistry , 2024 , 2 ( 9 ): 428 - 446 .

Xu J N , Meng J , Hu Y , et al . Electrocatalytic lignin valorization into aromatic products via oxidative cleavage of C α –C β bonds [J ] . Research , 2023 , 6 : 288 .

Yang Y L , Kong L Y , Xia Z C , et al . Dual-vacancy-induced selective oxidative cleavage of C α –C β bonds for the electrocatalytic depolymerization of lignin [J ] . Journal of the American Chemical Society , 2025 , 147 ( 39 ): 35924 - 35934 .

Li P F , Zhang J Q , Liu S S , et al . Multimetal synergy in an iron–cobalt–nickel hydroxide electrocatalyst for electro-oxidative lignin depolymerization to produce value-added aromatic chemicals [J ] . Chemical Communications , 2024 , 60 ( 73 ): 9982 - 9985 .

Waura-angkura L , Matsagar B M , Lee K , et al . Efficient lignin depolymerization by continuous flow microreactor-assisted electrochemical advanced oxidation in water/co-solvent system [J ] . Green Chemistry , 2024 , 26 ( 4 ): 1889 - 1900 .

He Y Q , Zeng X , Lu Z R , et al . Aqueous electrocatalytic hydrogenation depolymerization of lignin β-O-4 linkage via selective C aryl –O(C) bond cleavage: the regulation of adsorption [J ] . Journal of the American Chemical Society , 2024 , 146 ( 46 ): 32022 - 32031 .

Lindenbeck L M , Barra V C , Dahlhaus S , et al . Organic chemicals from wood: selective depolymerization and dearomatization of lignin via aqueous electrocatalysis [J ] . ChemSusChem , 2024 , 17 ( 9 ): e202301617 .

Lindenbeck L , Brand S , Stallmann F , et al . Silver-catalyzed aqueous electrochemical valorization of soda lignin into aliphatics and phenolics [J ] . Polymers , 2024 , 16 ( 23 ): 3325 .

Liu Y B , Lindenbeck L M , Frauscher M , et al . Nickel-driven electrochemical upgrading of kraft lignin to value-added aliphatic and phenolic products [J ] . Molecules , 2025 , 30 ( 12 ): 2544 .

Ren P D , Shi L , Kan Z W , et al . Molecular palladium catalyst enabling efficient electrochemical C-C bond cleavage within lignin model compounds [J ] . Catalysis Science & Technology , 2024 , 14 ( 4 ): 973 - 979 .

Huang Z H , Yu Z H , Guo Z G , et al . Selective cleavage of C β–O–4 bond for lignin depolymerization via paired-electrolysis in an undivided cell [J ] . Angewandte Chemie International Edition , 2024 , 63 ( 37 ): e202407750 .

Zhang J F , Suo C C , Hao X C , et al . Radical-mediated Cα-Cβ cleavage by ZnIn 2 S 4 -based heterojunction materials in photo-electro-catalysis [J ] . Journal of Catalysis , 2025 , 448 : 116189 .

Liu B W , Qi Y , Qiu X Q , et al . Photoelectrocatalytic pathway for the preparation of power-effective aviation fuel precursors from lignin [J ] . Advanced Functional Materials , 2025 , 35 ( 20 ): 2421552 .

Morais D F S , Sena L M G , Ribeiro J M , et al . Insights into photoelectrocatalytic lignin oxidation to value-added products using a niobium-doped titanium dioxide photoanode [J ] . Green Chemistry , 2025 , 27 ( 22 ): 6537 - 6555 .

Li W L , Huang J S , Liao Y H , et al . Rectifying lattice strain for selective photoelectrocatalytic conversion of lignin to aromatic acids [J ] . Journal of Materials Science & Technology , 2026 , 249 : 56 - 66 .

Mohan M , Simmons B A , Sale K L , et al . Multiscale molecular simulations for the solvation of lignin in ionic liquids [J ] . Scientific Reports , 2023 , 13 : 271 .

Zhou M , Fakayode O A , Ren M N , et al . Laccase-catalyzed lignin depolymerization in deep eutectic solvents: challenges and prospects [J ] . Bioresources and Bioprocessing , 2023 , 10 ( 1 ): 21 .

Qin Y X , Li D , Mahmood S , et al . Microwave-assisted oxidative degradation of lignin catalyzed by hydrogen peroxide–alkaline ionic liquid system [J ] . Catalysts , 2025 , 15 ( 4 ): 367 .

Khan S , Rauber D , Veerabagu U , et al . Tailored lignin fractions via ionic liquid pretreatment for sustainable polymer systems [J ] . Molecules , 2025 , 30 ( 12 ): 2630 .

Li H C , Li D Q , He Y , et al . Unleashing the potential of lignin with innovative trifunctional binary deep eutectic solvent strategy: Isolation of uncondensed lignin [J ] . Science Advances , 2025 , 11 ( 27 ): eadv7299 .

Wang Z W , Liu Y Z , Barta K , et al . The effect of acidic ternary deep eutectic solvent treatment on native lignin [J ] . ACS Sustainable Chemistry & Engineering , 2022 , 10 ( 38 ): 12569 - 12579 .

Kim J , Kim C , Jeong C , et al . Integrated process for lignin depolymerization and nanoparticle production using deep eutectic solvent [J ] . Scientific Reports , 2025 , 15 : 11770 .

Yan B C , Lin X Y , Xiao J , et al . Comparative study for the separation and depolymerization behavior of lignin from different separation methods [J ] . Fuel , 2024 , 358 : 130145 .

Giardino G J , Wang H Y , Niu J , et al . From technical lignin to native lignin: Depolymerization, functionalization, and applications [J ] . Chemical Physics Reviews , 2024 , 5 ( 2 ): 021302 .

李治宇 , 逯炀炀 , 王文文 , 等 . " 木质素优先解聚"策略下生物质定向解聚研究进展 [J ] . 农业工程学报 , 2024 , 40 ( 1 ): 129 - 141 .

Li Z Y , Lu Y Y , Wang W W , et al . Progress in directed biomass depolymerisation under the “lignin-first depolymerisation” strategy [J ] . Transactions of the Chinese Society of Agricultural Engineering , 2024 , 40 ( 1 ): 129 - 141 .

刘国祥 , 孙恩惠 , 黄红英 , 等 . 木质素优先解聚对碳水化合物影响的研究进展 [J ] . 生物质化学工程 , 2024 , 58 ( 6 ): 73 - 84 .

Liu G X , Sun E H , Huang H Y , et al . Advances in research based on the effects of preferential lignin depolymerisation on carbohydrates [J ] . Biomass Chemical Engineering , 2024 , 58 ( 6 ): 73 - 84 .

Liu Z Z , Li H L , Gao X Y , et al . Rational highly dispersed ruthenium for reductive catalytic fractionation of lignocellulose [J ] . Nature Communications , 2022 , 13 : 4716 .

Song Q , Wang F , Cai J Y , et al . Lignin depolymerization (LDP) in alcohol over nickel-based catalysts via a fragmentation-hydrogenolysis process [J ] . Energy & Environmental Science , 2013 , 6 ( 3 ): 994 - 1007 .

Sun Z H , Bottari G , Afanasenko A , et al . Complete lignocellulose conversion with integrated catalyst recycling yielding valuable aromatics and fuels [J ] . Nature Catalysis , 2018 , 1 ( 1 ): 82 - 92 .

Zhou H , Xiang Q , Guo Z R , et al . Efficient Pt 1 Ni single-atom alloy catalyst for hydrogen-free catalytic fractionation of lignocellulose [J ] . Nature Communications , 2026 , 17 : 4316 .

Wang Q , Xiao L P , Xu Q , et al . Reductive catalytic fractionation of lignocellulose over copper phyllosilicate nanotube catalysts [J ] . Cell Reports Physical Science , 2024 , 5 ( 7 ): 102055 .

Zhu Y T , Liao Y H , Lu L Y , et al . Oxidative catalytic fractionation of lignocellulose to high-yield aromatic aldehyde monomers and pure cellulose [J ] . ACS Catalysis , 2023 , 13 ( 12 ): 7929 - 7941 .

Cui Y B , Weeda E P , Omolabake S , et al . Oxidative catalytic fractionation of lignocellulosic biomass using a Co-N-P-C catalyst and one-step isolation of aromatic monomers via centrifugal partition chromatography [J ] . ACS Sustainable Chemistry & Engineering , 2024 , 12 ( 26 ): 9795 - 9804 .

Zhu L Y , Cui C H , Auersvald M , et al . Unveiling the mechanism of reductive catalytic fractionation via online high-resolution mass spectrometry: insights into lignin valorization [J ] . ACS Sustainable Chemistry & Engineering , 2025 , 13 ( 14 ): 5434 - 5443 .

Rahman M M , Reza T . Hydrothermal liquefaction of structurally diverse lignins: insights into biocrude yield, fuel properties, and reaction mechanisms [J ] . Energies , 2025 , 18 ( 17 ): 4773 .

Wörner M , Barsuhn A , Zevaco T , et al . From pulp to aromatic Products-Reaction pathways of lignin depolymerization [J ] . Energy & Fuels , 2024 , 38 ( 7 ): 6020 - 6035 .

于士杰 , 赵鹏 , 刘茂清 , 等 . 温度-压力解耦对木质素水热过程中结构变化及解聚产物的影响 [J ] . 燃料化学学报(中英文) , 2023 , 51 ( 8 ): 1106 - 1113 .

Yu S J , Zhao P , Liu M Q , et al . Effects of decoupled temperature and pressure on the hydrothermal process of lignin [J ] . Journal of Fuel Chemistry and Technology , 2023 , 51 ( 8 ): 1106 - 1113 .

Fontecha-Cámara M Á , Delgado-Blanca I , Mañas-Villar M , et al . Extraction and depolymerization of lignin from different agricultural and forestry wastes to obtain building blocks in a circular economy framework [J ] . Polymers , 2024 , 16 ( 14 ): 1981 .

Ye J M , Yu H P , Jia Z W , et al . Promotion of lignin depolymerization and cellulose utilization via the coupling effects of DDQ pre-oxidation and HCOOH extraction [J ] . Chemical Engineering Journal , 2024 , 493 : 152267 .

Gao J , Cao Y , Zhang Y T , et al . Highly efficient lignin depolymerization and enhanced bio-oil upgrading via in-situ hydrogenation: Impact of lignin structure [J ] . Chemical Engineering Journal , 2024 , 498 : 155837 .

De Santi A , Monti S , Barcaro G , et al . New mechanistic insights into the lignin β-O-4 linkage acidolysis with ethylene glycol stabilization aided by multilevel computational chemistry [J ] . ACS Sustainable Chemistry & Engineering , 2021 , 9 ( 5 ): 2388 - 2399 .

Zhai Z Q , Lu Y M , Ding W L , et al . Ionic liquids for sustainable lignin biorefinery: from dissolution mechanisms to electrocatalytic upgrading [J ] . Green Chemistry , 2026 , 28 ( 23 ): 9548 - 9573 .

Schröder A , Wu R J , Eklund P , et al . Active lignin stabilization in lignocellulosic biomass fractionation: mechanisms and advancements [J ] . Green Chemistry , 2026 , 28 ( 15 ): 6562 - 6584 .

Brienza F , Cannella D , Montesdeoca D , et al . A guide to lignin valorization in biorefineries: traditional, recent, and forthcoming approaches to convert raw lignocellulose into valuable materials and chemicals [J ] . RSC Sustainability , 2024 , 2 ( 1 ): 37 - 90 .

Questell-Santiago Y M , Galkin M V , Barta K , et al . Stabilization strategies in biomass depolymerization using chemical functionalization [J ] . Nature Reviews Chemistry , 2020 , 4 ( 6 ): 311 - 330 .

Gong Z G , Shuai L . Lignin condensation, an unsolved mystery [J ] . Trends in Chemistry , 2023 , 5 ( 3 ): 163 - 166 .

Kim K H , Kim C S . Recent efforts to prevent undesirable reactions from fractionation to depolymerization of lignin: toward maximizing the value from lignin [J ] . Frontiers in Energy Research , 2018 , 6 : 92 .

Komatsu T , Yokoyama T . Revisiting the condensation reaction of lignin in alkaline pulping with quantitativity partIII: predominant formation of α-β-type over α-5-type condensation product in soda cooking treatments of apocynol and creosol [J ] . Journal of Wood Science , 2022 , 68 ( 1 ): 60 .

Zhang C F , Li H J , Lu J M , et al . Promoting lignin depolymerization and restraining the condensation via an oxidation–hydrogenation strategy [J ] . ACS Catalysis , 2017 , 7 ( 5 ): 3419 - 3429 .

Lan W , Luterbacher J S . Preventing lignin condensation to facilitate aromatic monomer production [J ] . Chimia , 2019 , 73 ( 7/8 ): 591 - 598 .

Shuai L , Amiri M T , Questell-Santiago Y M , et al . Formaldehyde stabilization facilitates lignin monomer production during biomass depolymerization [J ] . Science , 2016 , 354 ( 6310 ): 329 - 333 .

Mu X L , Han Z , Liu C B , et al . Mechanistic insights into formaldehyde-blocked lignin condensation: a DFT study [J ] . The Journal of Physical Chemistry C , 2019 , 123 ( 14 ): 8640 - 8648 .

Zhao Y L , Zhao D Q , He J P , et al . Protective fractionation of highly uncondensed lignin with high purity and high yield: new insights into propanediol-blocked lignin condensation [J ] . Green Chemistry , 2025 , 27 ( 16 ): 4244 - 4258 .

Zhao D Q , He J P , Zhao Y L , et al . Efficient and protective upgrading of uncondensed lignin extraction with high yield and high purity: mechanistic insights into lewis acid catalysis coupled with PEG stabilization [J ] . Biomacromolecules , 2025 , 26 ( 7 ): 4675 - 4689 .

Lindenbeck L M , Brand S , Schatz F , et al . One-pot electrocatalytic lignin depolymerization with in situ extraction: a feasible approach for the production of biomass-based oils [J ] . Green Chemistry , 2025 , 27 ( 33 ): 9927 - 9936 .

Shao S B , Wang X Z , Li W B , et al . A mini review on photocatalytic lignin conversion into monomeric aromatic compounds [J ] . Catalysis Science & Technology , 2025 , 15 ( 4 ): 962 - 987 .

Tan F F . Photocatalytic valorization of lignin: radical-mediated scission of recalcitrant bonds to aromatics [J ] . RSC Advances , 2025 , 15 ( 27 ): 21947 - 21961 .

Pei Z F , Liu X F , Chen J S , et al . Research progress on lignin depolymerization strategies: a review [J ] . Polymers , 2024 , 16 ( 17 ): 2388 .

Lindenbeck L M , Barra V C , Beele B B , et al . Revisiting the electrocatalyst role on lignin depolymerization [J ] . Advanced Energy and Sustainability Research , 2024 , 5 ( 10 ): 2400130 .

De Saegher T , Atanasova B , Vermeir P , et al . Enhancing the performance of heterogeneous palladium based catalysts in the mild reductive depolymerization of soda lignin through addition of a non-noble metal and tuning of the preparation strategy [J ] . RSC Sustainability , 2024 , 2 ( 5 ): 1551 - 1567 .

Nilza N , Salam M D . Recent advances in generation of bioproducts from lignin: a comprehensive review [J ] . Discover Sustainability , 2025 , 6 ( 1 ): 1083 .

Daelemans B , Sridharan B , Jusner P , et al . From lignin to market: a technical and economic perspective of reductive depolymerization approaches [J ] . Green Chemistry , 2025 , 27 ( 42 ): 13160 - 13178 .

Ranganathan P . Techno-economic analysis of lignin-first biorefinery using reductive catalytic fractionation of rice straw [J ] . Bioresource Technology Reports , 2026 , 33 : 102617 .

Xu Y L , Rios D C , Wang S , et al . Process design and techno-economic analysis for the lignin oil solvent recovery and purification process [J ] . Journal of Cleaner Production , 2024 , 434 : 139999 .

Jusner P , Sridharan B , Daelemans B , et al . Assessing the potential for upscaling the continuous production of lignin oils through reductive catalytic depolymerization [J ] . Chemical Engineering Journal , 2024 , 499 : 156474 .

Lian P F , Liu S J , Ma Z H , et al . Lignin oxidative depolymerization to phenolic compounds in a continuous-flow manufacturing platform [J ] . Industrial Crops and Products , 2024 , 212 : 118376 .

Sun D Y , Liu H J , Wu H W , et al . Oxidative depolymerization of lignin in a Fixed-Bed tubular membrane reactor [J ] . Separation and Purification Technology , 2025 , 364 : 132478 .

Wu X Y , De bruyn M , Barta K . Deriving high value products from depolymerized lignin oil, aided by (bio)catalytic funneling strategies [J ] . Chemical Communications , 2023 , 59 ( 66 ): 9929 - 9951 .

Pei F Y , Liu L J , Zhu H E , et al . Recent advances in lignocellulose-based monomers and their polymerization [J ] . Polymers , 2023 , 15 ( 4 ): 829 .

简雅婷 , 余强 , 陈小燕 , 等 . 木质素制备生物液体燃料进展 [J ] . 化工进展 , 2021 , 40 ( S2 ): 109 - 116 .

Jian Y T , Yu Q , Chen X Y , et al . Progress in the preparation of liquid biofuels from lignin [J ] . Chemical Industry and Engineering Progress , 2021 , 40 ( S2 ): 109 - 116 .

Wang X F , Wang M Y , Li M S , et al . Selective hydrodeoxygenation of lignin via aryl ether C–O bond cleavage: Cs-mediated Cu surface engineering [J ] . ACS Catalysis , 2024 , 14 ( 24 ): 18774 - 18785 .

毕培燕 . 木质素定向合成航空煤油环烷烃和芳烃组分研究 [D ] . 合肥：中国科学技术大学 , 2015 .

Bi P Y . Directional synthesis of jet and diesel fuel range cycloparaffins and aromatics using lignin [D ] . Hefei : University of Science and Technology of China , 2015 .

Dong L , Fang Z Q , Yuan Q B , et al . Selective utilization of formaldehyde stabilizing additive and methoxy groups in lignin for the production of high-carbon-number arenes [J ] . Chinese Journal of Catalysis , 2025 , 68 : 356 - 365 .

Yu J J , Gao Y , Hu L D , et al . Production of aromatic hydrocarbons from lignin via catalytic gas-phase pyrolysis over a PtMo/Ti@Si core-shell catalyst [J ] . Energy , 2026 , 351 : 140815 .

Wang N , Liao Z J , Deng Y X , et al . Coordination-engineered Ni-Pd on lignin-derived carbon for the upgrading of technical lignin toward aromatic-rich aviation fuel precursors [J ] . Advanced Functional Materials , 2026 , 36 ( 49 ): e75770 .

Subbotina E , Souza L R , Zimmerman J , et al . Room temperature catalytic upgrading of unpurified lignin depolymerization oil into bisphenols and butene-2 [J ] . Nature Communications , 2024 , 15 : 5892 .

Castillo-Garcia A A , Kappe C O , Cantillo D , et al . Aniline derivatives from lignin under mild conditions enabled by electrochemistry [J ] . ChemSusChem , 2024 , 17 ( 3 ): e202301374 .

Liu M Y , Dyson P J . Direct conversion of lignin to functionalized diaryl ethers via oxidative cross-coupling [J ] . Nature Communications , 2023 , 14 : 2830 .

Zhang Z L , Guo G , Yang H Z , et al . One-pot catalytic cascade for the depolymerization of the lignin β-O-4 motif to non-phenolic dealkylated aromatics [J ] . Angewandte Chemie International Edition , 2024 , 63 ( 49 ): e202410382 .

Dong Y G , Dong L , Gu X L , et al . Sustainable production of active pharmaceutical ingredients from lignin-based benzoic acid derivatives via “demand orientation” [J ] . Green Chemistry , 2023 , 25 ( 10 ): 3791 - 3815 .

Qi S Y , Zhang X W , Zhang Z Y , et al . Valorizing lignin to bioactive natural compounds [J ] . ChemSusChem , 2025 , 18 ( 23 ): e202501617 .

Liu L X , Wang X T , Wu Y Y , et al . Chemoenzymatic platform with coordinated cofactor self-circulation for lignin valorization [J ] . Nature Synthesis , 2025 , 4 ( 9 ): 1151 - 1160 .

Yu O , Kim K H . Lignin to materials: a focused review on recent novel lignin applications [J ] . Applied Sciences , 2020 , 10 ( 13 ): 4626 .

靳汇奇 , 贾文超 , 盛雪茹 , 等 . 木质素羟基化改性及其在聚氨酯合成中的应用 [J ] . 中国造纸 , 2021 , 40 ( 10 ): 108 - 119 .

Jin H Q , Jia W C , Sheng X R , et al . Hydroxylation of lignin and its application in synthesis of polyurethane [J ] . China Pulp & Paper , 2021 , 40 ( 10 ): 108 - 119 .

郭瑶 , 李瀛 , 李春苗 , 等 . 生物质热解油酚醛树脂制备与应用研究进展 [J ] . 材料导报 , 2025 , 39 ( S2 ): 718 - 723 .

Guo Y , Li Y , Li C M , et al . Research progress in preparation and application of biomass pyrolysis oil phenolic resin [J ] . Materials Reports , 2025 , 39 ( S2 ): 718 - 723 .

Su Z M , Twilton J , Hoyt C B , et al . Ni- and Ni/Pd-catalyzed reductive coupling of lignin-derived aromatics to access biobased plasticizers [J ] . ACS Central Science , 2023 , 9 ( 2 ): 159 - 165 .

王冠华 . 汽爆秸秆木质素分级及其材料的制备 [D ] . 北京：中国科学院研究生院(过程工程研究所) , 2015 .

Wang G H . Fractionation of lignin from steam-exploded corn stalk and lignin-based materials preparation [D ] . Beijing : Institute of Process Engineering, Chinese Academy of Sciences , 2015 .

陈涛 , 李思宇 , 曾奇斌 , 等 . 木质素解聚产物改性三聚氰胺系陶瓷添加剂的研究及应用 [J ] . 硅酸盐通报 , 2025 , 44 ( 7 ): 2608 - 2616 .

Chen T , Li S Y , Zeng Q B , et al . Research and application of lignin depolymerisation products modified melamine-based ceramic additives [J ] . Bulletin Of The Chinese Ceramic Society , 2025 , 44 ( 7 ): 2608 - 2616 .

Li P H , Yu J D , Wang M K , et al . Preparation of symmetrical capacitors from lignin-derived phenol and PANI composites with good electrical conductivity [J ] . International Journal of Molecular Sciences , 2023 , 24 ( 10 ): 8661 .

Li Y B , Meng X Z , Meng R Q , et al . Valorization of homogeneous linear catechyl lignin: opportunities and challenges [J ] . RSC Advances , 2023 , 13 ( 19 ): 12750 - 12759 .

Long G C , Liu X H , Li X , et al . CO 2 cycloaddition with lignin-derived oxidized styrene catalyzed by the halogen-free N, O Co-doped carbon-based materials [J ] . ChemCatChem , 2025 , 17 ( 21 ): e01216 .

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