Production process for ursolic acid

LI Kaiquan; CHEN Wu; LI Xiangyi

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Production process for ursolic acid

更新时间：2026-03-26

- Production process for ursolic acid
- CIESC Journal Vol. 57, Issue 2, (2006)
- 作者机构：
  
  宜春学院生物工程研究所
- 作者简介：
- 基金信息：
- DOI：
  CLC：
- Online First：25 February 2006，
  
  Published：2006
- 稿件说明：
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LI Kaiquan, CHEN Wu, LI Xiangyi. Production process for ursolic acid[J]. CIESC Journal, 2006, 57(2).
DOI：

LI Kaiquan, CHEN Wu, LI Xiangyi. Production process for ursolic acid[J]. CIESC Journal, 2006, 57(2). DOI：

摘要

Abstract

Production of ursolic acid

the anti-hepatitis effective composition from natural plant

Sambucus chinensis Lindl.was carried out and the scale-up preparation technology was studied.Extraction of the herb Sambucus chinensis Lindl.was extracted in reflux with 7 volume times of refluxing ethanol at 80℃ for 1 h for two times.The extract was purified with a selt-made specific impurity remover “YCXY-1” to yield ursolic acid of high purity.A new “Extraction/Gelation” technology for the production of ursolic acid was developed. The specific impurity remover “YCXY-1” showed high effectiveness in purification. The purity of the mass-produced ursolic acid was up to 99.8%. The chemical structure of the product was confirmed by the physicochemical constants and spectroscopic identification. The production of high-purity ursolic acid was optimized with natural plant as raw material and with only ethanol as extracting solvent. The difficulties such as isolation and impurity removal were addressed effectively. The novel technology is reasonable

convenient

practical

low-cost

high-yield

suitable for mass production.

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