Synthesis, characterization, scavenging free radical and bacteriostasis characteristics of calcium-genistein complex

刘潇

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Synthesis, characterization, scavenging free radical and bacteriostasis characteristics of calcium-genistein complex

更新时间：2025-12-10

- Synthesis, characterization, scavenging free radical and bacteriostasis characteristics of calcium-genistein complex
- CIESC Journal Issue 11, (2010)
- 作者机构：
  
  1. 东北农业大学理学院应用化学系
  2. 乳品科学教育部重点实验室
- 作者简介：
- 基金信息：
- DOI：
  CLC：
- Online First：05 November 2010，
  
  Published：05 November 2010
- 稿件说明：
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刘潇. Synthesis, characterization, scavenging free radical and bacteriostasis characteristics of calcium-genistein complex[J]. CIESC Journal, 2010, (11).
DOI：

刘潇. Synthesis, characterization, scavenging free radical and bacteriostasis characteristics of calcium-genistein complex[J]. CIESC Journal, 2010, (11). DOI：

摘要

Abstract

By using genistein and calcium hydroxide as raw materials

calcium-genistein complex was synthesized and characterized with IR spectra

UV-spectra

thermal analysis and NMR spectrum. The biological activities of the complex were studied by means of pyrogallol autoxidation

Fenton reaction

orthophenanthroline photometry and DPPH free radical. And also the bacteriostasis activities of the ligand and its complex against three different types of bacteria

namely: Escherichia coli，Pseudomonas aeruginosa，Listeria monocytogenes were studied. The results showed that in calcium-genistein complex Ca2+ was coordinated by 5-OH and 4-CO groups of genistein and the molecular formula was［Ca(C15H9O5)2］·2H2O. At the same concentration

the scavenging effects of Gen-Ca on superoxide radical and anti-hydroxy free radical showed better activity than the free ligand

but anti-DPPH free radical ability was not so obvious. The ligand and its complex had certain bacteriostasis effect

and the complex showed increased activity compared to the respective ligand.

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