CRYSTALLIZATION PROCESS OF PHENYLPYRUVIC ACID SODIUM SALT

Fan Weiping; Wu Yue; Ouyang Pingkai; Zhu Jianliang(Department of Biotechnology and Bioengineering

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CRYSTALLIZATION PROCESS OF PHENYLPYRUVIC ACID SODIUM SALT

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- CRYSTALLIZATION PROCESS OF PHENYLPYRUVIC ACID SODIUM SALT
- CIESC Journal Issue 1, (1998)
- 作者机构：
  
  南京化工大学生物工程与科学系!南京210009,南京化工大学生物工程与科学系!南京210009,南京化工大学生物工程与科学系!南京210009,南京化工大学生物工程与科学系,南京,210009
- 作者简介：
- 基金信息：
- DOI：
  CLC： Q02
- Online First：25 February 1998，
  
  Published：25 February 1998
- 稿件说明：
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Fan Weiping, Wu Yue, Ouyang Pingkai, et al. CRYSTALLIZATION PROCESS OF PHENYLPYRUVIC ACID SODIUM SALT[J]. CIESC Journal, 1998, (1).
DOI：

Fan Weiping, Wu Yue, Ouyang Pingkai, et al. CRYSTALLIZATION PROCESS OF PHENYLPYRUVIC ACID SODIUM SALT[J]. CIESC Journal, 1998, (1). DOI：

摘要

Abstract

The mixing-precipitation process for producing phenylpyruvic acid sodium salt(PPNa) by neutralization of phenylpyruic acid(PPA) with aqueous sodium hydroxide in a semi-batch stirred tank was studied.The effects of mixing characteristics and chemical characteristics on the precipitation process were investigated experimentally.It was found that the crystals growth rate and morphology obviously changed due to ripening.Crystal redissolution agglomeration and solvent inclusion also changed the purity of PPNa product considerably.

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