Ni-Mo-B and Co-Ni-Mo-B amorphous catalysts were prepared by chemical reduction method with sodium borohydride aqueous solution.The resulting materials were characterized by BET，SEM，XRD，XPS and DSC.Using phenol as the model compound，the hydrodeoxygenation（HDO）performances of the catalysts were evaluated.With the addition of Co，the particle size became smaller and the electron transfer from Ni to B was promoted.The HDO activity was lower for Ni-Mo-B than for Co-Ni-Mo-B for which phenol conversion 98% and HDO selectivity up to 93% at temperature 523 K were obtained.The aromatic content in the refining of bio-oil was lower than that of European regulation.Although the HDO selectivity goes up with the increase of reaction temperature，the conversion went down and the content of intermediates increased because of unstability of amorphous structure at high temperature.