Axial liquid and slurry velocity distributions in a slurry bubble column were measured by Pavlov tube under the condition of high superficial gas velocity（0.12—0.93 m8226;s-1）and large solid concentration（0.1—0.3 based on slurry phase）.Experiment results showed that axial liquid and slurry velocity distributions became steeper with increasing superficial gas velocity and scale of bubble columns.On the contrary，velocity profiles did not obviously change with increasing solid concentration.Then normalized velocity profiles under different conditions could be approximately fitted by a single curve，which indicated that center-line velocity was a key parameter to predict bubble column scale-up effects.Under the experimental condition，Nottenkamper’s correlation was suitable for calculating the center-line velocity.Furthermore a one-dimension hydrodynamic model was presented to predict velocity distributions in the slurry bubble column.The model computational results agreed well with experimental data.