Delayed release of chloramphenicol from poly（2-hydroxyethylmethacrylate-co-acrylamide）hydrogels

CUI Yingde; LI Xinming

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Delayed release of chloramphenicol from poly（2-hydroxyethylmethacrylate-co-acrylamide）hydrogels

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- Delayed release of chloramphenicol from poly（2-hydroxyethylmethacrylate-co-acrylamide）hydrogels
- CIESC Journal Issue 9, Pages: 2416-2418(2008)
- 作者机构：
  
  仲恺农业工程学院化学化工学院
- 作者简介：
- 基金信息：
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- Online First：05 September 2008，
  
  Published：05 September 2008
- 稿件说明：
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CUI Yingde, LI Xinming. Delayed release of chloramphenicol from poly（2-hydroxyethylmethacrylate-co-acrylamide）hydrogels[J]. CIESC Journal, 2008, (9): 2416-2418.
DOI：

CUI Yingde, LI Xinming. Delayed release of chloramphenicol from poly（2-hydroxyethylmethacrylate-co-acrylamide）hydrogels[J]. CIESC Journal, 2008, (9): 2416-2418. DOI：

摘要

采用本体共聚法制备poly(HEMA-co-AAm)（甲基丙烯酸羟乙酯与丙烯酰胺共聚物）水凝胶，采用恒温释放方法研究了poly(HEMA-co-AAm)水凝胶对氯霉素的缓释作用。结果表明，随水凝胶中AAm组分的含量增大，水凝胶对氯霉素的吸收量增大，氯霉素的释放速率也相应增大；随缓释介质的pH值下降，氯霉素的释放速率增大；在初始释放阶段，氯霉素的迁移速率随水凝胶中AAm组分的含量增大而增大，但随后并无明显影响。

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Related Institution

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