By considering the characteristics of information generation of chemical industry product configuration model，a new method of constructing chemical equipment configuration model based on axiomatic design theory was presented. In this method，functional domain mapping into physical domain was introduced，functional requirements with constraints were defined as function constraint integrated component（FCIC），design parameters with feature were defined as structure feature integrated component（SFIC），and the configuration model based on SFIC was constructed by establishing database and the characteristic relationship of SFIC features. Axiomatic design made configuration modeling more scientific，and helped the designer decide more quickly and accurately. Finally，a case study of configuration design for air separation equipment was presented.