Preparation method and experimental apparatus of microcapsules by using microfluids digitalization technology

ZHANG Xiaole; HOU Liya; ZHANG Weiyi

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Preparation method and experimental apparatus of microcapsules by using microfluids digitalization technology

更新时间：2025-12-10

- Preparation method and experimental apparatus of microcapsules by using microfluids digitalization technology
- CIESC Journal Issue 8, Pages: 2133-2137(2007)
- 作者机构：
  
  南京理工大学微系统研究室
- 作者简介：
- 基金信息：
- DOI：
  CLC：
- Online First：05 August 2007，
  
  Published：05 August 2007
- 稿件说明：
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ZHANG Xiaole, HOU Liya, ZHANG Weiyi. Preparation method and experimental apparatus of microcapsules by using microfluids digitalization technology[J]. CIESC Journal, 2007, (8): 2133-2137.
DOI：

ZHANG Xiaole, HOU Liya, ZHANG Weiyi. Preparation method and experimental apparatus of microcapsules by using microfluids digitalization technology[J]. CIESC Journal, 2007, (8): 2133-2137. DOI：

摘要

提出了一种新的基于微流体数字化技术的单分散微胶囊制备方法。该方法通过对微喷嘴施加小幅可控的脉冲惯性力，完成对微胶囊材料的小份分割、数字化传输及喷射。使用该方法进行了海藻酸钠对芝麻油微胶囊化的实验。制备过程中，每个驱动脉冲喷射出一颗微胶囊乳化液液滴。制备的节拍既可以是连续的，也可以是编码的，因此可以对制备过程进行有效的控制。通过改变微喷嘴内径可以制备出微米级系列尺寸的规整化的微胶囊，微胶囊粒径分布窄。

Abstract

A new method of preparing monodisperse microcapsules was proposed on the basis of digitalization of microfluids technology.By employing this method

the microcapsule material was divided into micro-droplets

digitally transported and jetted by means of disturbing micropipette with controllable pulse inertial force.In the experiments

sesame oil was microencapsulated with sodium alginate.In the process of microencapsulation

every disturbing pulse produced a single emulsion-solvent droplet.The rhythm of microencapsulation could be either sequential or encoded

therefore the process of microencapsulation could be effectively controlled.By changing the inside diameter of the micropipette

standardized microcapsules of different micron scale sizes were produced

and the size distribution was narrow.The number of microcapsules could be calculated by counting the time.

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