Effects of matrix material content on soluble drug release from matrix

GAO Yingchun; ZHANG Liang; BIAN Zhengzhong

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Effects of matrix material content on soluble drug release from matrix

更新时间：2025-12-10

- Effects of matrix material content on soluble drug release from matrix
- CIESC Journal Issue 10, Pages: 2024-2028(2005)
- 作者机构：
  
  1. 第四军医大学,陕西,西安,710032
  2. 西安交通大学生命科学与技术学院,陕西,西安,710049
- 作者简介：
- 基金信息：
- DOI：
  CLC：
- Online First：25 October 2005，
  
  Published：25 October 2005
- 稿件说明：
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GAO Yingchun, ZHANG Liang, BIAN Zhengzhong. Effects of matrix material content on soluble drug release from matrix[J]. CIESC Journal, 2005, (10): 2024-2028.
DOI：

GAO Yingchun, ZHANG Liang, BIAN Zhengzhong. Effects of matrix material content on soluble drug release from matrix[J]. CIESC Journal, 2005, (10): 2024-2028. DOI：

摘要

Abstract

The effects of different matrix material contents on the release of soluble drug’s mixed matrix were studied.With dissolution as guideline

and Captopril as model drug the effect of matrix material contents on the release of Captopril from hydrophilic gel matrix

wax matrix and mixed matrix were compared.The content of the matrix material had greater influence on the release of Captopril from mixed matrix than that from former single matrix. Moreover

the effect of Compritol 888 contents was more significant than that of HPMC K4M in mixed matrix.

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